5-Amino-2'-deoxyuridine (monohydrochloride)
5-Amino-2'-deoxyuridine (monohydrochloride) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
73446-40-9
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-amino-2-deoxyuridine-monohydrochloride.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H](CO)O[C@@H](N2C(NC(C(N)=C2)=O)=O)C1.Cl
Molecular Formula
C9H14ClN3O5
Molecular Weight
279.68
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL
Cytokeratin 7 (KRT7/1198), CF568 conjugate, 0.1mg/mL
