Vitamin D3-d7
Product Specifications
UNSPSC Description
Vitamin D3-d7 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells[1][2].
Target Antigen
Bacterial; Endogenous Metabolite; Isotope-Labeled Compounds; VD/VDR
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Metabolic Enzyme/Protease;Others;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Purity
97.0
Solubility
10 mM in DMSO
Smiles
C=C1CC[C@@H](C/C1=C/C=C2[C@@]([H])([C@@]3(CCC/2)C)CC[C@]3([H])[C@@H](CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C)O
Molecular Weight
391.68
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Nazik Al-Hashimi, et al. Cholecalciferol|[3]Laura Bergadà, et al. Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma. Lab Invest. 2014 Jun;94(6):608-22|[4]Hiroki Yoshioka, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12(4):e0176524.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light, stored under nitrogen
Clinical Information
No Development Reported
CAS Number
1627523-19-6
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