Vitamin D3-d7

Vitamin D3-d7 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells[1][2].

Product Specifications

CAS Number

[1627523-19-6]

UNSPSC

12352211

Hazard Statement

H300+H310, H372

Target

Bacterial; Endogenous Metabolite; Isotope-Labeled Compounds; VD/VDR

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease

Purity

97.00

Solubility

10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)

Smiles

C=C1CC[C@@H](C/C1=C/C=C2[C@@]([H])([C@@]3(CCC/2)C)CC[C@]3([H])[C@@H](CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C)O

Molecular Formula

C27H37D7O

Molecular Weight

391.68

Precautions

H300+H310, H372

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Nazik Al-Hashimi, et al. Cholecalciferol|[3]Laura Bergadà, et al. Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma. Lab Invest. 2014 Jun;94 (6) :608-22|[4]Hiroki Yoshioka, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12 (4) :e0176524.