Fmoc-Gly3-VC-PAB-MMAE
Product Specifications
UNSPSC Description
Fmoc-Gly3-VC-PAB-MMAE is a Drug-Linker Conjugates for ADC. Fmoc-Gly3-VC-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker[1].
Target Antigen
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-gly3-vc-pab-mmae.html
Solubility
10 mM in DMSO
Smiles
CC[C@@H]([C@H](N(C)C([C@@H](NC([C@@H](N(C)C(OCC1=CC=C(C=C1)NC([C@@H](NC([C@@H](NC(CNC(CNC(CNC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O)=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)=O)C(C)C)=O)C(C)C)=O)[C@H](OC)CC(N5[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@H](C6=CC=CC=C6)O)C)=O)C)CCC5)=O)C
Molecular Weight
1516.82
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153976/Fmoc-Gly3-VC-PAB-MMAE-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153976/
Clinical Information
No Development Reported
Curated Selection
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