PF-06478939 (TFA)
Product Specifications
UNSPSC Description
PF-06478939 TFA is a non-brain-penetrating peptide that is an agonist at oxytocin (OT) receptor and vasopressin receptor with EC50 values of 0.01 nM and 0.078 nM, respectively[1].
Target Antigen
Oxytocin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pf-06478939-tfa.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C[C@@H](C(N[C@@H]([C@H](CC)C)C(N[C@H](C(N[C@H]2CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](N)CSSC[C@@H](C(N3CCC[C@H]3C(N[C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCCCCCCCCCCCC)=O)=O)C(NCC(N)=O)=O)=O)=O)NC2=O)=O)C=C1.O=C(O)C(F)(F)F.[x]
References & Citations
[1]Modi ME, et al. Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing. J Pharmacol Exp Ther. 2016 Aug;358(2):164-72.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153964A/PF-06478939-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153964A/
Clinical Information
No Development Reported
Curated Selection
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