USP7-IN-12
USP7-IN-12 (compound 1) is a potent and orally active Usp7 inhibitor with an IC50 value of 3.67 nM. USP7-IN-12 shows antiproliferative activity[1].
Product Specifications
CAS Number
2763698-01-5
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp7-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CC2=CC3=NC=CC(C4=CC(Cl)=CC5=C4N(CC6(CCNCC6)F)C=C5)=C3S2)C(C7C1C7(C)C)=O
Molecular Formula
C29H28ClFN4O2S
Molecular Weight
551.07
References & Citations
[1]Deng Hou, et al. Usp7 inhibitor. WO2022048498A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
USP7
Frequently Asked Questions
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