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USP7-IN-12

USP7-IN-12 (compound 1) is a potent and orally active Usp7 inhibitor with an IC50 value of 3.67 nM. USP7-IN-12 shows antiproliferative activity[1].

Product Specifications

CAS Number

2763698-01-5

UNSPSC

12352005

Target

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/usp7-in-12.html

Solubility

10 mM in DMSO

Smiles

O=C1N(CC2=CC3=NC=CC(C4=CC(Cl)=CC5=C4N(CC6(CCNCC6)F)C=C5)=C3S2)C(C7C1C7(C)C)=O

Molecular Formula

C29H28ClFN4O2S

Molecular Weight

551.07

References & Citations

[1]Deng Hou, et al. Usp7 inhibitor. WO2022048498A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

USP7

Frequently Asked Questions

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