PROTAC PTPN2 degrader-2 (TFA)
PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases[1].
Product Specifications
CAS Number
2912307-39-0
UNSPSC
12352005
Target
Phosphatase; PROTACs
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/protac-ptpn2-degrader-2-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C3C(N1[C@@H]4C(NC(CC4)=O)=O)=CC=C(C5CCN(CC5)C(NC6=CC(CS(=O)(N7C(C)(C[C@H](CC7)NC8=CC(C9=C(C(OCC(O)=O)=C(S9)C(O)=O)Cl)=CC=C8)C)=O)=CC=C6)=O)C3=CC=C2.OC(C(F)(F)F)=O
Molecular Formula
C51H50ClF3N6O13S2
Molecular Weight
1111.55
References & Citations
[1]Protein tyrosine phosphatase targeting ligands.WO2023019166.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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