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PROTAC PTPN2 degrader-2 (TFA)

PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases[1].

Product Specifications

CAS Number

2912307-39-0

UNSPSC

12352005

Target

Phosphatase; PROTACs

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; PROTAC

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/protac-ptpn2-degrader-2-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C3C(N1[C@@H]4C(NC(CC4)=O)=O)=CC=C(C5CCN(CC5)C(NC6=CC(CS(=O)(N7C(C)(C[C@H](CC7)NC8=CC(C9=C(C(OCC(O)=O)=C(S9)C(O)=O)Cl)=CC=C8)C)=O)=CC=C6)=O)C3=CC=C2.OC(C(F)(F)F)=O

Molecular Formula

C51H50ClF3N6O13S2

Molecular Weight

1111.55

References & Citations

[1]Protein tyrosine phosphatase targeting ligands.WO2023019166.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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