B-Raf IN 14
B-Raf IN 14 (Comp 25) is a BRAF inhibitor with IC50 value of 11.08 μM, which can be used in cancer-related research[1].
Product Specifications
CAS Number
[326918-98-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/b-raf-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C(N)CSC(N1CC2=CC=CC(Br)=C2)=NC(N(C)C(N3)=O)=C1C3=O
Molecular Formula
C15H14BrN5O3S
Molecular Weight
424.27
Precautions
H302, H315, H319
References & Citations
[1]Cheng Luo, et al. Identification of BRAF inhibitors through in silico screening. J Med Chem. 2008 Oct 9;51 (19) :6121-6127.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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