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MMP-9-IN-7

MMP-9-IN-7 is a potent MMP9 inhibitor with an IC50 of 0.52 μM in proMMP9/MMP3 P126 activation assay. MMP-9-IN-7 is extracted from patent WO2012162468 (example 59), and can be used for MMP9/MMP13 mediated syndrome research[1].

Product Specifications

CAS Number

[333746-76-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mmp-9-in-7.html

Solubility

10 mM in DMSO

Smiles

O=C(C)NC1=NC(C)=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)S1

Molecular Formula

C16H15ClN4O2S2

Molecular Weight

394.90

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Paul Francis Jackson, et al. Thiazol derivatives as pro -matrix metalloproteinase inhibitors. Patent WO2012162468.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MMP-9

Available Sizes

Curated Selection

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