TLR8 agonist 6
TLR8 agonist 6 (Compound A) is a TLR8 agonist, with an EC50 of 0.052 μM. TLR8 agonist 6 induces IL-12p40 production in human PBMC (EC50: 0.031 μM) . TLR8 agonist 6 can be used in the research of virus resistance, infection resistance, autoimmunity, tumor, etc[1].
Product Specifications
CAS Number
2616605-55-9
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tlr8-agonist-6.html
Solubility
10 mM in DMSO
Smiles
CN(C)C(C(C=N1)=CC2=C1C(N[C@](CNC(C)=O)(C)CCCC)=NC(N)=N2)=O
Molecular Formula
C19H29N7O2
Molecular Weight
387.48
References & Citations
[1]Liang Bo, et al. 2-aminopyrimidine compounds and pharmaceutical composition and application thereof. Patent. CN112390795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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