TLR8 agonist 6
TLR8 agonist 6 (Compound A) is a TLR8 agonist, with an EC50 of 0.052 μM. TLR8 agonist 6 induces IL-12p40 production in human PBMC (EC50: 0.031 μM) . TLR8 agonist 6 can be used in the research of virus resistance, infection resistance, autoimmunity, tumor, etc[1].
Product Specifications
CAS Number
2616605-55-9
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tlr8-agonist-6.html
Solubility
10 mM in DMSO
Smiles
CN(C)C(C(C=N1)=CC2=C1C(N[C@](CNC(C)=O)(C)CCCC)=NC(N)=N2)=O
Molecular Formula
C19H29N7O2
Molecular Weight
387.48
References & Citations
[1]Liang Bo, et al. 2-aminopyrimidine compounds and pharmaceutical composition and application thereof. Patent. CN112390795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC422357 20 µg
Glutamine Synthetase (GLuL) (NM_001033056) Human Over-expression Lysate
Sign In for Pricing
View Details 
