KRAS G12C inhibitor 59
KRAS G12C inhibitor 59 is a KRAS G12C inhibitor with anticancer effects (WO2023036282A1, compound II) [1].
Product Specifications
CAS Number
[2914919-88-1]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-59.html
Solubility
10 mM in DMSO
Smiles
O=C(C(F)=C)N1CCN(C2=NC(OC[C@]34N(C[C@H](F)C4)CCC3)=NC5=C2CO[C@H](C6=C(C(F)(F)F)C(C)=CC(N)=C6F)C5)C[C@@H]1CC#N.O.O
Molecular Formula
C32H39F6N7O5
Molecular Weight
715.69
References & Citations
[1]Yangyang Yu, et al. Crystal form of pyrimidine heterocyclic compound and preparation method therefor. WO2023036282A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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