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KRAS G12C inhibitor 59

KRAS G12C inhibitor 59 is a KRAS G12C inhibitor with anticancer effects (WO2023036282A1, compound II) [1].

Product Specifications

CAS Number

[2914919-88-1]

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-g12c-inhibitor-59.html

Solubility

10 mM in DMSO

Smiles

O=C(C(F)=C)N1CCN(C2=NC(OC[C@]34N(C[C@H](F)C4)CCC3)=NC5=C2CO[C@H](C6=C(C(F)(F)F)C(C)=CC(N)=C6F)C5)C[C@@H]1CC#N.O.O

Molecular Formula

C32H39F6N7O5

Molecular Weight

715.69

References & Citations

[1]Yangyang Yu, et al. Crystal form of pyrimidine heterocyclic compound and preparation method therefor. WO2023036282A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

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