PSB-1901
PSB-1901 is a potent A2B adenosine receptor (A2BAR) antagonist with Kis of 0.0835 nM and 0.131 nM for human and mouse A2BARs respectively. PSB-1901 can be used for the research of cancer[1].
Product Specifications
CAS Number
2332835-02-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/psb-1901.html
Purity
96.33
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1NC2=C(C(N1CCC)=O)NC(C3=CC=C(S(=O)(N4CCN(CC4)C5=CC=C(C=C5)Br)=O)C=C3)=N2
Molecular Formula
C24H25BrN6O4S
Molecular Weight
573.46
Precautions
H302, H315, H319
References & Citations
[1]Jiang J, et al. A2B Adenosine Receptor Antagonists with Picomolar Potency. J Med Chem. 2019 Apr 25;62 (8) :4032-4055.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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