BTA-EG4

BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance the neurotoxicity of amyloid peptides in catalase-overexpressing neuronal cells, and can be used in the study of neurodegenerative diseases[1].

Product Specifications

CAS Number

921193-28-4

UNSPSC

12352005

Target

Amyloid-β; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bta-eg4.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C2N=C(C3=CC=C(NCCOCCOCCOCCO)C=C3)SC2=C1

Molecular Formula

C22H28N2O4S

Molecular Weight

416.53

References & Citations

[1]Amrutha Chilumuri, et al. Benzothiazole Aniline Tetra (ethylene glycol) and 3-Amino-1,2,4-triazole Inhibit Neuroprotection against Amyloid Peptides by Catalase Overexpression in Vitro.Amrutha Chilumuri, Mark Odell, and Nathaniel G. N. Milton.ACS Chemical Neuroscience 2013 4 (11), 1501-1512.