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ISIS 14803

ISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell culture.

Product Specifications

CAS Number

223603-41-6

UNSPSC

12352208

Target

HCV

Type

Oligonucleotides

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/isis-14803.html

Solubility

10 mM in H2O

Smiles

[ISIS14803]

References & Citations

[1]McHutchison JG, Patel K, Pockros P, et al. A phase I trial of an antisense inhibitor of hepatitis C virus (ISIS 14803), administered to chronic hepatitis C patients. J Hepatol. 2006;44 (1) :88-96. doi:10.1016/j.jhep.2005.09.009

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 2

Frequently Asked Questions

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