Anivamersen (sodium)
Anivamersen sodium is an RNA aptamer to reverse the anticoagulant effect of the parenteral factor IXa inhibitor pegnivacogin. REG1 is a novel anticoagulation system consisting of pegnivacogin, an RNA aptamer inhibitor of coagulation factor IXa, and anivamersen, a complementary sequence reversal oligonucleotide.
Product Specifications
CAS Number
959716-31-5
UNSPSC
12352208
Target
Factor Xa
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/anivamersen-sodium.html
Solubility
10 mM in H2O
Smiles
[Anivamersen(sodium)]
Molecular Formula
C157H194N56Na14O103P14
Molecular Weight
5269.10
References & Citations
[1]Lincoff AM, Mehran R, Povsic TJ, et al. Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI) : a randomised clinical trial [published correction appears in Lancet. 2016 Mar 19;387 (10024) :1162. Boudoulas, Dean [corrected to Boudoulas, Konstantinos D.]]. Lancet. 2016;387 (10016) :349-356. doi:10.1016/S0140-6736 (15) 00515-2
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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