Alcudacigib
Alcudacigib (Compound 9) is an inhibitor of DGKζ. Alcudacigib can be used for research in cancer related to immunocyte activation or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody[1].
Product Specifications
CAS Number
[2660218-70-0]
Product Name Alternative
DGKζ-IN-1
UNSPSC
12352005
Target
DGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dgkζ-in-1.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=C(N2C[C@@H](CCC2)CN)C(NC(C3=CSC(C4=CN=NC=C4)=N3)=O)=CC=C1OC5=CC=CC=C5)F
Molecular Formula
C27H25F3N6O2S
Molecular Weight
554.59
References & Citations
[1]Watanabe H, et al. Preparation of pyridazinyl-thiazolecarboxamide compound as DGKζ inhibitor. World Intellectual Property Organization, WO2021132422 A1. 2021-07-01.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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