Talibegron (hydrochloride)
Talibegron hydrochloride (ZD2079 hydrochloride) is a potent β3-adrenoceptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Talibegron hydrochloride has potent vasorelaxant effect[1].
Product Specifications
CAS Number
[178600-17-4]
Product Name Alternative
ZD2079 (hydrochloride)
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/talibegron-hydrochloride.html
Purity
99.63
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)CC1=CC=C(OCCNC[C@H](O)C2=CC=CC=C2)C=C1.[H]Cl
Molecular Formula
C18H22ClNO4
Molecular Weight
351.82
References & Citations
[1]Hanna Kozłowska, et al. Atypical beta-adrenoceptors, different from beta 3-adrenoceptors and probably from the low-affinity state of beta 1-adrenoceptors, relax the rat isolated mesenteric artery. Br J Pharmacol. 2003 Sep;140 (1) :3-12.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
β adrenergic receptor
Available Sizes
Curated Selection
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