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DL-Gabaculine (hydrochloride)

DL-Gabaculine hydrochloride is a neurotoxin that irreversibly inhibits bacterial pyridoxal phosphate linked γ-aminobutyric acid-α-ketoglutaric acid transaminase with a Ki of 2.86 μM[1].

Product Specifications

CAS Number

59556-17-1

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dl-gabaculine-hydrochloride.html

Purity

99.90

Solubility

DMSO : ≥ 20mg/mL

Smiles

O=C(C1=CC=CC(N)C1)O.Cl

Molecular Formula

C7H10ClNO2

Molecular Weight

175.61

Precautions

H302, H315, H319, H335

References & Citations

[1]Rando R R. Mechanism of the irreversible inhibition of γ-aminobutyric acid-α-ketoglutaric acid transaminase by the neurotoxin gabaculine. Biochemistry, 1977, 16 (21) : 4604-4610.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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