DL-Gabaculine (hydrochloride)
DL-Gabaculine hydrochloride is a neurotoxin that irreversibly inhibits bacterial pyridoxal phosphate linked γ-aminobutyric acid-α-ketoglutaric acid transaminase with a Ki of 2.86 μM[1].
Product Specifications
CAS Number
59556-17-1
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dl-gabaculine-hydrochloride.html
Purity
99.90
Solubility
DMSO : ≥ 20mg/mL
Smiles
O=C(C1=CC=CC(N)C1)O.Cl
Molecular Formula
C7H10ClNO2
Molecular Weight
175.61
Precautions
H302, H315, H319, H335
References & Citations
[1]Rando R R. Mechanism of the irreversible inhibition of γ-aminobutyric acid-α-ketoglutaric acid transaminase by the neurotoxin gabaculine. Biochemistry, 1977, 16 (21) : 4604-4610.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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