JGK-068S
JGK-068S (compound I) is a potent EGFR inhibitor[1].
Product Specifications
CAS Number
[2490431-16-6]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jgk-068s.html
Solubility
10 mM in DMSO
Smiles
CN(CC1)CCN1C[C@@H]2OC3=CC(C(NC4=C(C(Br)=CC=C4)F)=NC=N5)=C5C=C3OC2
Molecular Formula
C22H23BrFN5O2
Molecular Weight
488.35
References & Citations
[1]Fritz Blatter, et al. Egfr inhibitor polymorph forms. WO2023049312A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
Curated Selection
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