JGK-068S

JGK-068S (compound I) is a potent EGFR inhibitor[1].

Product Specifications

CAS Number

[2490431-16-6]

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jgk-068s.html

Solubility

10 mM in DMSO

Smiles

CN(CC1)CCN1C[C@@H]2OC3=CC(C(NC4=C(C(Br)=CC=C4)F)=NC=N5)=C5C=C3OC2

Molecular Formula

C22H23BrFN5O2

Molecular Weight

488.35

References & Citations

[1]Fritz Blatter, et al. Egfr inhibitor polymorph forms. WO2023049312A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EGFR/ErbB1/HER1

Curated Selection

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