JAK-IN-28
JAK-IN-28 (Compound 111) is a JAK inhibitor. JAK-IN-28 can be used for research of cancer or inflammatory diseases[1].
Product Specifications
CAS Number
2445500-22-9
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jak-in-28.html
Solubility
10 mM in DMSO
Smiles
ClC1=CN=C(NC2=CN(C3CC3)N=C2)N=C1C4=CC=C(C=C4)C(N[C@@H](C)C#N)=O
Molecular Formula
C20H18ClN7O
Molecular Weight
407.86
References & Citations
[1]Wan Zhaokui, et al. Benzamides of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof. Patent. WO2020119819. 2020-06-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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