BTK-IN-25
Product Specifications
UNSPSC Description
BTK-IN-25 (Compound 71) is a BTK inhibitor (IC50: 0.77 nM). BTK-IN-25 inhibits the proliferation of DOHH2 cells (IC50: 1 nM)[1].
Target Antigen
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-in-25.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C=C(C=C1)OC2=C(C=CC=C2)F)F)C3=CNC4=NC=C(OCC)C(N[C@@H]5CC[C@H](OC5)CO)=C34
Molecular Weight
523.53
References & Citations
[1]Tan H, et al. Substituted pyrrolo[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cell proliferative disorders. World Intellectual Property Organization, WO2020239124 A1. 2020-12-03.|[2]Tan Haohan. Substituted pyrrolo [2,3-b ] pyridine and pyrazolo [3,4-b ] pyridine derivatives as protein kinase inhibitors. Patent. CN114008042.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153705/BTK-IN-25-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153705/
Clinical Information
No Development Reported
CAS Number
2562351-92-0
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