SORT-PGRN interaction inhibitor 3
SORT-PGRN interaction inhibitor 3 (Compound 13) is a SORT-PGRN interaction inhibitor (IC50: 0.17 μM) . SORT-PGRN interaction inhibitor 3 can be used for research of neurodegenerative diseases[1].
Product Specifications
CAS Number
2691846-87-2
UNSPSC
12352005
Target
Neurotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sort-pgrn-interaction-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)CC[C@@H](C(O)=O)NC(C1=CC(Cl)=CC(Cl)=C1)=O
Molecular Formula
C15H19Cl2NO3
Molecular Weight
332.22
References & Citations
[1]Stachel SJ, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30 (17) :127403.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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