PROTAC SOS1 degrader-4
PROTAC SOS1 degrader-4 (compound 10) is a potent SOS1 degrader. PROTAC SOS1 degrader-4 shows antiproliferative activity[1].
Product Specifications
UNSPSC
12352005
Target
PROTACs; Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-sos1-degrader-4.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(CC2CCC3(CCN(C(C4=CC=C(Cl)C(N5CCC(NC5=O)=O)=C4)=O)CC3)CC2)CC1)[C@H]6CC[C@H](C7=CC8=C(N[C@H](C)C9=CC=CC%10=C9CCS%10(=O)=O)N=C(C)N=C8C=C7OC)CC6
Molecular Formula
C53H65ClN8O7S
Molecular Weight
993.65
References & Citations
[1]ZhengQing Ye, et al. Sos1 degrading agent and preparation method therefor and application thereof. WO2022223033A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6122130-01 0.1 mL
CD30 (CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor Superfamily member 8 (TNFRSF8)) (APC)
Ask
View Details 
MBS6122130-02 5x 0.1 mL
CD30 (CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor Superfamily member 8 (TNFRSF8)) (APC)
Ask
View Details 