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PROTAC SOS1 degrader-4

Product Specifications

UNSPSC Description

PROTAC SOS1 degrader-4 (compound 10) is a potent SOS1 degrader. PROTAC SOS1 degrader-4 shows antiproliferative activity[1].

Target Antigen

PROTACs; Ras

Type

Reference compound

Related Pathways

GPCR/G Protein;MAPK/ERK Pathway;PROTAC

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-sos1-degrader-4.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCN(CC2CCC3(CCN(C(C4=CC=C(Cl)C(N5CCC(NC5=O)=O)=C4)=O)CC3)CC2)CC1)[C@H]6CC[C@H](C7=CC8=C(N[C@H](C)C9=CC=CC%10=C9CCS%10(=O)=O)N=C(C)N=C8C=C7OC)CC6

Molecular Weight

993.65

References & Citations

[1]ZhengQing Ye, et al. Sos1 degrading agent and preparation method therefor and application thereof. WO2022223033A1.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-153674/PROTAC-SOS1-degrader-4-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-153674/

Clinical Information

No Development Reported

Curated Selection

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