PROTAC SOS1 degrader-4
PROTAC SOS1 degrader-4 (compound 10) is a potent SOS1 degrader. PROTAC SOS1 degrader-4 shows antiproliferative activity[1].
Product Specifications
UNSPSC
12352005
Target
PROTACs; Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-sos1-degrader-4.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(CC2CCC3(CCN(C(C4=CC=C(Cl)C(N5CCC(NC5=O)=O)=C4)=O)CC3)CC2)CC1)[C@H]6CC[C@H](C7=CC8=C(N[C@H](C)C9=CC=CC%10=C9CCS%10(=O)=O)N=C(C)N=C8C=C7OC)CC6
Molecular Formula
C53H65ClN8O7S
Molecular Weight
993.65
References & Citations
[1]ZhengQing Ye, et al. Sos1 degrading agent and preparation method therefor and application thereof. WO2022223033A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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