SB-649701
SB-649701 is a potent human CCR8 antagonist, with a pIC50 of 7.7. AZ084 can be used for the research of asthma[1].
Product Specifications
CAS Number
935262-95-6
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sb-649701.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(C=C1)N=CC=C2[C@@H]3CN(C4CCN(CC4)CC5=CC6=CC=CC=C6N5)C(O3)=O
Molecular Formula
C27H28N4O3
Molecular Weight
456.54
References & Citations
[1]Jin J, et, al. Oxazolidinones as novel human CCR8 antagonists. Bioorg Med Chem Lett. 2007 Mar 15;17 (6) :1722-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR8
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