THR-β modulator-1

THR-β modulator-1 (compound 1a) is a potent thyroid hormone receptor β modulator. THR-β modulator-1 can be used in research of thyroid hormone receptor related disorders[1].

Product Specifications

CAS Number

2770373-00-5

UNSPSC

12352005

Target

Thyroid Hormone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/thr-β-modulator-1.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(CC[C@H]2C)C(OC3=C(Cl)C=C(N4N=C(N)C(NC4=O)=O)C=C3Cl)=NN1

Molecular Formula

C17H14Cl2N6O4

Molecular Weight

437.24

References & Citations

[1]David CM, et, al. Bicyclic pyridazinones and methods of use thereof. WO2022099060A2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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