THR-β modulator-1
THR-β modulator-1 (compound 1a) is a potent thyroid hormone receptor β modulator. THR-β modulator-1 can be used in research of thyroid hormone receptor related disorders[1].
Product Specifications
CAS Number
2770373-00-5
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/thr-β-modulator-1.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(CC[C@H]2C)C(OC3=C(Cl)C=C(N4N=C(N)C(NC4=O)=O)C=C3Cl)=NN1
Molecular Formula
C17H14Cl2N6O4
Molecular Weight
437.24
References & Citations
[1]David CM, et, al. Bicyclic pyridazinones and methods of use thereof. WO2022099060A2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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