BET bromodomain inhibitor 3

BET bromodomain inhibitor 3 is BET bromodomain inhibitor. BET bromodomain inhibitor 3 has inhibitory effect against BrdT with Ki value of > 40 µM. BET bromodomain inhibitor 3 can be used for the research of contraception, cancer, and heart disease[1].

Product Specifications

CAS Number

[854137-39-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bet-bromodomain-inhibitor-3.html

Purity

97.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1OCC2=C1C(C3=CC=C(C)C=C3)C(C(N(C)C(N4C)=O)=O)=C4N2

Molecular Formula

C18H17N3O4

Molecular Weight

339.35

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Ayoub AM, et al. BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen [published correction appears in J Med Chem. 2017 Jul 27;60 (14) :6458]. J Med Chem. 2017;60 (12) :4805-4817.