HDAC8-IN-4
Product Specifications
UNSPSC Description
HDAC8-IN-4 is a selective inhibitor of HDAC8. HDAC8-IN-4 inhibits HDAC8 and HDAC3 with IC50s of 0.15 and 12 μM[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac8-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC(C2=CSC(CSC3=CC=CC=C3)=N2)=C1)NO
Molecular Weight
342.44
References & Citations
[1]Suzuki T, et al. Design, synthesis, and biological activity of NCC149 derivatives as histone deacetylase 8-selective inhibitors. ChemMedChem. 2014 Mar;9(3):657-64.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153583/HDAC8-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153583/
Clinical Information
No Development Reported
CAS Number
1600528-05-9
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