BacPROTAC-1
Product Specifications
UNSPSC Description
BacPROTAC-1 is a mSA BacPROTAC degrader. BacPROTAC-1 binds mSA and ClpCNTD with high affinity (KDs of 3.9 and 2.8 μM, respectively)[1].
Target Antigen
Bacterial; PROTACs
Type
Reference compound
Related Pathways
Anti-infection;PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bacprotac-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCC[C@H](NC(CCOCCOCCNC(CCOCCOCCNC(CCOCCOCCNC([C@H](CCCNC(NP(O)(O)=O)=N)NC(C)=O)=O)=O)=O)=O)C(N)=O)CCCC[C@@H]1SC[C@@H]([C@@H]1N2)NC2=O
Molecular Weight
1127.25
References & Citations
[1]Morreale FE, et al. BacPROTACs mediate targeted protein degradation in bacteria. Cell. 2022 Jun 23;185(13):2338-2353.e18.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153575/BacPROTAC-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153575/
Clinical Information
No Development Reported
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