Homo-BacPROTAC6
Homo-BacPROTAC6 is a ClpC1NTD BacPROTAC degrader and can targets ClpC2. Homo-BacPROTAC7 efficiently kill M. tuberculosis[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; PROTACs
Type
Reference compound
Related Pathways
Anti-infection; PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/homo-bacprotac6.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N(C)[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC1=CN(CC2=CN(CCOCCOCCOCCOCCN3C=C(CN4C=C(C[C@@H]5NC([C@@H](NC([C@@H](N(C)C([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@H](C[C@@H](C)CO)N(C)C5=O)=O)C)=O)[C@@H](C6=CC=CC=C6)OC)=O)=O)CC(C)C)=O)C(C)C)=O)C7=C4C=CC=C7)N=N3)N=N2)C8=C1C=CC=C8)C9=O)=O)=O)CC(C)C)=O)C(C)C)[C@@H](NC([C@H](C)NC([C@H](C[C@H](CO)C)N9C)=O)=O)[C@H](OC)C%10=CC=CC=C%10
Molecular Formula
C112H164N22O22
Molecular Weight
2170.63
References & Citations
[1]Hoi DM, et al. Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival. Cell. 2023 May 11;186 (10) :2176-2192.e22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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