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JAK1-IN-10

JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, is a potent and selective JAK1 inhibitor[1].

Product Specifications

CAS Number

2416858-88-1

UNSPSC

12352005

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jak1-in-10.html

Solubility

10 mM in DMSO

Smiles

N#CCC1CCN(CC1)N2C(N)=NC3=CNC4=NC=CC4=C32

Molecular Formula

C15H17N7

Molecular Weight

295.34

References & Citations

[1]Shen Wang, et al. Preparation method of cyano-substituted cyclic hydrazine derivative and its application. World Intellectual Property Organization, WO2021051899 A1. 2021-03-25.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

JAK1

Frequently Asked Questions

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