JAK1-IN-10
JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, is a potent and selective JAK1 inhibitor[1].
Product Specifications
CAS Number
2416858-88-1
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jak1-in-10.html
Solubility
10 mM in DMSO
Smiles
N#CCC1CCN(CC1)N2C(N)=NC3=CNC4=NC=CC4=C32
Molecular Formula
C15H17N7
Molecular Weight
295.34
References & Citations
[1]Shen Wang, et al. Preparation method of cyano-substituted cyclic hydrazine derivative and its application. World Intellectual Property Organization, WO2021051899 A1. 2021-03-25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK1
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