ROCK-IN-6
ROCK-IN-6 is a potent and selectiveROCK2 inhibitor with an IC50 of 2.19 nM. ROCK-IN-6 is extracted from patent WO2021164351 A1, example 7, has the potential for glaucoma and retinal diseases research[1].
Product Specifications
CAS Number
2489328-74-5
UNSPSC
12352005
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rock-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC2=CC=NC=C2S1)C(C(C=C3)=CC=C3OCC(O[N+]([O-])=O)CO[N+]([O-])=O)CN
Molecular Formula
C19H19N5O8S
Molecular Weight
477.45
References & Citations
[1]Shen wang et al. Nitrooxyderivative of rock kinase inhibitor. Patent WO2021164351 A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ROCK2
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