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ROCK-IN-6

ROCK-IN-6 is a potent and selectiveROCK2 inhibitor with an IC50 of 2.19 nM. ROCK-IN-6 is extracted from patent WO2021164351 A1, example 7, has the potential for glaucoma and retinal diseases research[1].

Product Specifications

CAS Number

2489328-74-5

UNSPSC

12352005

Target

ROCK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rock-in-6.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC2=CC=NC=C2S1)C(C(C=C3)=CC=C3OCC(O[N+]([O-])=O)CO[N+]([O-])=O)CN

Molecular Formula

C19H19N5O8S

Molecular Weight

477.45

References & Citations

[1]Shen wang et al. Nitrooxyderivative of rock kinase inhibitor. Patent WO2021164351 A1

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ROCK2

Frequently Asked Questions

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