Lp-PLA2-IN-14
Lp-PLA2-IN-14 (Compound 19) is an Lp-PLA2 inhibitor with a pIC50 of 8.4 against rhLp-PLA2. Lp-PLA2-IN-14 can be used for the research of neurodegenerative related diseases, such as Alzheimer Disease (AD), glaucoma, age-related macular degeneration (AMD) or cardiovascular diseases including atherosclerosis and the like[1].
Product Specifications
CAS Number
2756855-66-8
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lp-pla2-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(C2=C(N1CCC3)N3CCO2)OCC4=CC(F)=C(C(F)=C4)F
Molecular Formula
C16H14F3N3O3
Molecular Weight
353.30
References & Citations
[1]Zhenghua Gu, et al. Tricyclic pyrimidone compounds, preparation method, composition and application thereof. Patent CN113861220A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A
Frequently Asked Questions
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