NH2-UAMC1110
NH2-UAMC1110 is a UAMC1110 (HY-100684) derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors[1].
Product Specifications
CAS Number
[2758337-19-6]
UNSPSC
12352005
Target
Drug Derivative; Drug Intermediate; FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh2-uamc1110.html
Purity
99.86
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(OCCCCN)C=C3)=O
Molecular Formula
C21H23F2N5O3
Molecular Weight
431.44
References & Citations
[1]Euy Sung Moon, et al. Targeting fibroblast activation protein (FAP) : next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators. EJNMMI Radiopharm Chem. 2020 Jul 29;5 (1) :19.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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