NH2-UAMC1110

NH2-UAMC1110 is a UAMC1110 (HY-100684) derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors[1].

Product Specifications

CAS Number

[2758337-19-6]

UNSPSC

12352005

Target

Drug Derivative; Drug Intermediate; FAP

Type

Reference compound

Related Pathways

Immunology/Inflammation; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nh2-uamc1110.html

Purity

99.86

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(OCCCCN)C=C3)=O

Molecular Formula

C21H23F2N5O3

Molecular Weight

431.44

References & Citations

[1]Euy Sung Moon, et al. Targeting fibroblast activation protein (FAP) : next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators. EJNMMI Radiopharm Chem. 2020 Jul 29;5 (1) :19.