HSP90-IN-21
HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. falciparum (Pf3D7 and PfDd2 strains), cytotoxicity of human liver hepatocellular carcinoma cell line (HepG2), respectively[1].
Product Specifications
CAS Number
[2521791-38-6]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hsp90-in-21.html
Solubility
10 mM in DMSO
Smiles
ClC(C=C1)=CC=C1/C=C/C(NCCN2C3=CC(OC)=CC=C3C4=CC=NC(C)=C42)=O
Molecular Formula
C24H22ClN3O2
Molecular Weight
419.90
References & Citations
[1]Marina Marinovi, et al. ćNovel Harmicines with Improved Potency against Plasmodium. Molecules. 2020 Sep 23;25 (19) :4376
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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