HSP90-IN-21

HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. falciparum (Pf3D7 and PfDd2 strains), cytotoxicity of human liver hepatocellular carcinoma cell line (HepG2), respectively[1].

Product Specifications

CAS Number

[2521791-38-6]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hsp90-in-21.html

Solubility

10 mM in DMSO

Smiles

ClC(C=C1)=CC=C1/C=C/C(NCCN2C3=CC(OC)=CC=C3C4=CC=NC(C)=C42)=O

Molecular Formula

C24H22ClN3O2

Molecular Weight

419.90

References & Citations

[1]Marina Marinovi, et al. ćNovel Harmicines with Improved Potency against Plasmodium. Molecules. 2020 Sep 23;25 (19) :4376

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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