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HSP90-IN-21

Product Specifications

UNSPSC Description

HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. falciparum (Pf3D7 and PfDd2 strains), cytotoxicity of human liver hepatocellular carcinoma cell line (HepG2), respectively[1].

Target Antigen

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hsp90-in-21.html

Solubility

10 mM in DMSO

Smiles

ClC(C=C1)=CC=C1/C=C/C(NCCN2C3=CC(OC)=CC=C3C4=CC=NC(C)=C42)=O

Molecular Weight

419.90

References & Citations

[1]Marina Marinovi, et al. ćNovel Harmicines with Improved Potency against Plasmodium. Molecules. 2020 Sep 23;25(19):4376

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-153547/HSP90-IN-21-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-153547/

Clinical Information

No Development Reported

CAS Number

2521791-38-6

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