STING agonist-31

STING agonist-31 is a STING agonist, with EC50 values of 0.24 and 39.51 μM for h-STING and m-STING. STING agonist-31 has antitumor efficiency[1].

Product Specifications

CAS Number

[2719001-44-0]

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sting-agonist-31.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OCCCN4CCOCC4)=C3N2C/C=C/CN5C6=C(OC)C=C(C7=NN=CN7)C=C6N=C5NC(C8=CC(C)=NN8CC)=O

Molecular Formula

C43H51N15O6

Molecular Weight

873.96

References & Citations

[1]Song Z, et al. Structure-Activity Relationship Study of Amidobenzimidazole Analogues Leading to Potent and Systemically Administrable Stimulator of Interferon Gene (STING) Agonists. J Med Chem. 2021 Feb 11;64 (3) :1649-1669.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-14094H 0.1 mL

Mouse Monoclonal IGF-I R/IGF1R Antibody (IGF1R/4667) [HRP]

Ask

View Details

A25539-100UG 100 µg

HPSE Antibody

Ask

View Details

MBS8803393-01 48 Well

Human ERN1 (Endoplasmic Reticulum To Nucleus Signalling 1) ELISA Kit

Ask

View Details

MBS8803393-02 96 Well

Human ERN1 (Endoplasmic Reticulum To Nucleus Signalling 1) ELISA Kit

Ask

View Details

MBS8803393-03 5x 96 Well

Human ERN1 (Endoplasmic Reticulum To Nucleus Signalling 1) ELISA Kit

Ask

View Details

MBS8803393-04 10x 96 Well

Human ERN1 (Endoplasmic Reticulum To Nucleus Signalling 1) ELISA Kit

Ask

View Details