AP-C7

AP-C7 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII) with a pIC50 of 5.0. AP-C7 only weakly inhibits cGKII-dependent anion secretion[1].

Product Specifications

CAS Number

[2234275-84-2]

UNSPSC

12352005

Target

PKG

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ap-c7.html

Solubility

10 mM in DMSO

Smiles

N1(C2=CC=C(C3=NC(NCC4=CC=CO4)=NC=C3)C=C2)C=CN=C1

Molecular Formula

C18H15N5O

Molecular Weight

317.34

References & Citations

[1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293 (21) :8173-8181.