AP-C7
AP-C7 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII) with a pIC50 of 5.0. AP-C7 only weakly inhibits cGKII-dependent anion secretion[1].
Product Specifications
CAS Number
[2234275-84-2]
UNSPSC
12352005
Target
PKG
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ap-c7.html
Solubility
10 mM in DMSO
Smiles
N1(C2=CC=C(C3=NC(NCC4=CC=CO4)=NC=C3)C=C2)C=CN=C1
Molecular Formula
C18H15N5O
Molecular Weight
317.34
References & Citations
[1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293 (21) :8173-8181.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153541/AP-C7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153541/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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