PROTAC BTK Degrader-3
Product Specifications
UNSPSC Description
PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. PROTAC BTK Degrader-3 has the potential for B-cell malignancies, including chronic lymphoid malignancies research[1].
Target Antigen
Btk; PROTACs
Type
Reference compound
Related Pathways
PROTAC;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-btk-degrader-3.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC=C(N3CC(C3)N4CC(C4)N5CCC(CC5)N6N=C(C7=C6N=CN=C7N)C8=CC=C(OC9=CC=CC=C9)C=C8)C=C2C(N1C%10C(NC(CC%10)=O)=O)=O
Molecular Weight
752.82
References & Citations
[1]Zhangchen, et al. Salt of compound for degrading btk, crystal form thereof, and use thereof in medicine. Patent WO2022052950A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153536/PROTAC-BTK-Degrader-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153536/
Clinical Information
No Development Reported
CAS Number
2563861-90-3
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