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GRL-1720

GRL-1720 is a potent SARS-CoV-2 Mpro inhibitor with an EC50 value of 15 µM. GRL-1720 shows anti-SARS-CoV2 activity[1].

Product Specifications

CAS Number

[2835511-03-8]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/grl-1720.html

Purity

98.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C2CCNC2=CC=C1)OC3=CC(Cl)=CN=C3

Molecular Formula

C14H11ClN2O2

Molecular Weight

274.70

References & Citations

[1]Hattori SI, et al. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nat Commun. 2021 Jan 28;12 (1) :668.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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