GRL-1720
GRL-1720 is a potent SARS-CoV-2 Mpro inhibitor with an EC50 value of 15 µM. GRL-1720 shows anti-SARS-CoV2 activity[1].
Product Specifications
CAS Number
[2835511-03-8]
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/grl-1720.html
Purity
98.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C2CCNC2=CC=C1)OC3=CC(Cl)=CN=C3
Molecular Formula
C14H11ClN2O2
Molecular Weight
274.70
References & Citations
[1]Hattori SI, et al. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nat Commun. 2021 Jan 28;12 (1) :668.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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