What is the catalog number for ISIS 5132?

The catalog number for ISIS 5132 is HY-153490.

What sizes are available for ISIS 5132?

ISIS 5132 is available in the following size(s): 1 Each.

Is ISIS 5132 in stock?

ISIS 5132 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ISIS 5132?

ISIS 5132 is manufactured by QuantiMol.

What is the estimated delivery time for ISIS 5132?

Estimated delivery time for ISIS 5132 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ISIS 5132?

The safety data sheet for ISIS 5132 is available here: http://file.medchemexpress.com/batch_PDF/HY-153490/.

ISIS 5132

ISIS 5132 is a 20-base phosphorothioate oligonucleotide that specifically down-regulates c-raf expression.

Product Specifications

CAS Number

177075-18-2

Product Name Alternative

CGP 69846A; ISIS 9271

UNSPSC

12352208

Target

Raf

Type

Oligonucleotides

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/isis-5132.html

Solubility

10 mM in H2O

Smiles

[ISIS5132]

References & Citations

[1]Rudin CM, Holmlund J, Fleming GF, et al. Phase I Trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer. Clin Cancer Res. 2001;7 (5) :1214-1220.|[2]Tolcher AW, Reyno L, Venner PM, et al. A randomized phase II and pharmacokinetic study of the antisense oligonucleotides ISIS 3521 and ISIS 5132 in patients with hormone-refractory prostate cancer. Clin Cancer Res. 2002;8 (8) :2530-2535.