Cimdelirsen (sodium)
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
Product Specifications
CAS Number
2131025-83-5
Product Name Alternative
ISIS 766720 (sodium) ; IONIS-GHR-LRx (sodium)
UNSPSC
12352208
Target
GHR; Small Interfering RNA (siRNA)
Type
Oligonucleotides
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cimdelirsen-sodium.html
Solubility
10 mM in H2O
Smiles
[Cimdelirsen(sodium)]
Molecular Formula
C296H415N83Na20O152P20S15
Molecular Weight
8688.55 (free acid)
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Frequently Asked Questions
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